Accompanying texts should be consulted for further details. There are no adequate and well controlled studies in pregnant women.Ĭorticosteroids have been shown to impair fertility in male rats.ĪU TGA pregnancy category A: Drugs which have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the fetus having been observed.ĪU TGA pregnancy category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human fetus or neonate without causing malformations. Maternal pulmonary edema has been reported with inhibition of uterine contractions and fluid overload. There is the possibility of adrenal cortex suppression in newborns with maternal long term use at higher doses however, the short term use of corticosteroids antepartum for the prevention of respiratory distress syndrome does not seem to pose a risk. Untreated adrenal insufficiency during pregnancy has been associated with poor outcomes in both mothers and infants. This drug has been used without reports of adverse outcomes in women with adrenal insufficiency. Teratogenicity including increased incidence of cleft palate have occurred in animal studies, however, the relevance to humans has been questioned. Hydrocortisone Pregnancy and Breastfeeding Warningsīrand names: A-Hydrocort, Alkindi Sprinkle, Colocort, Cortef, Cortenema, Cortifoam, Hydrocortone, Hydrocortone Phosphate, Solu-Cortef
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